(012) 420-2075

Tubulin dysfunction in Alzheimer’s Disease

BY Yigael Powrie

The MSc study entailed investigating the relationship between the neuronal microtubulin cytoskeleton and the protein degradation process called autophagy, a system known to be dysfunctional in Alzheimer’s disease. We sought to elucidate previously unknown molecular events that occur prior to the onset of cell death brought on by induced autophagy dysfunction and in doing so highlight potentially new targets for therapeutic intervention in the treatment of Alzheimer’s disease.


Stellenbosch University


IMAGE: Micrograph of a mouse brain cell stained with fluorescent antibodies to visualize the microtubulin cytoskeleton (Green), Spastin (Red) - a protein known to interact with microtubulin and the nucleus (Blue).

 July 05, 2017
Comments (0)
MSSA Newsletter
Yigael Powrie

Leave a comment

Keep me updated?

Comments are moderated.
Be the first person to comment.

Contact Us

Tel & Address Info

Tel:  012 841 3643

Fax:  012 841 2227

Council for Scientific and Industrial Research,
1-Meiring Naude Road, Brummeria
Pretoria, 0001, South Africa

Operation Hours:

Monday - Friday 

08h00 - 16h30


Want to join the society? Complete the easy to use online form and enjoy the benefits of being a member of MSSA!

Who doesn't like cookies?
This website uses cookies to ensure you get the best experience. Read more...