(012) 420-2075

Latest developments in high pressure freezing

Andreas Nowak

Leica – Microsystems, Ernst-Leitz-Str. 17-37, 35578 Wetzlar, Germany
Email: Andreas.Nowak@leica-microsystems.com


Leica Microsystems has launched a High-Pressure Freezer with Fully Integrated Light Stimulation system. High pressure freezing is currently the only method for preserving aqueous samples in their native state. The Leica EM ICE enables users to cryo-fixate samples without introducing structural alteration, so that samples imaged with an electron microscope yield close-to-native state images at nanometer resolution. Additionally, the Leica EM ICE gives researchers the possibility to design novel experiments with the combination of high pressure freezing and light stimulation. High-pressure freezing combined with light stimulation can reveal intricate changes in fine structure or fundamental processes in life science and industry research. The instrument enables users to synchronize high-pressure freezing and light stimulation with the precision of a millisecond, capturing dynamic phenomena to further analyze it at nanometer resolution. Details of the latest developments in high pressure freezing using the LEICA EM ICE will be presented.

 November 06, 2015
Comments (0)
Technical Forum 2015

Leave a comment

Keep me updated?

Comments are moderated.
Be the first person to comment.

Contact Us

Tel & Address Info

Tel:  012 841 3643

Fax:  012 841 2227

Council for Scientific and Industrial Research,
1-Meiring Naude Road, Brummeria
Pretoria, 0001, South Africa

Operation Hours:

Monday - Friday 

08h00 - 16h30


Want to join the society? Complete the easy to use online form and enjoy the benefits of being a member of MSSA!

Who doesn't like cookies?
This website uses cookies to ensure you get the best experience. Read more...